Article
Growth-Coupled Carotenoids Production Using Adaptive Laboratory Evolution.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
Reyes Luis H, Kao Katy C
Abstract excerpt
Adaptive laboratory evolution is a powerful technique for strain development. However, the target phenotypes using this strategy have been limited by the required coupling of the phenotype-of-interest with fitness or survival, and thus adaptive evolution is generally not used to improve product formation. If the desired product confers a benefit to the host, then adaptive evolution can be an effective approach to...
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