Article
Adaptive laboratory evolution of Saccharomyces cerevisiae CEN.PK 113-7D to enhance ethanol tolerance.
FEMS yeast research - 30 Jan 2025
Sheikhi Fatemeh, Babaei Mahsa, Rostami Khosrow, Azin Mehrdad, Asadollahi Mohammad Ali, Ghiaci Payam, Ebrahimi Mansour, Feizi Amir, Borodina Irina
Abstract excerpt
Saccharomyces cerevisiae is a widely used yeast for industrial production of ethanol. However, elevated ethanol, temperature, and osmotic stress adversely affect fermentation efficiency. In this study, adaptive laboratory evolution for S. cerevisiae CEN.PK 113-7D on higher concentrations of ethanol was performed. After 144 days, the maximum specific growth rate (µmax) increased from 0.0240 to 0.1150 h-1 for the...
Read the complete abstract on PubMedTopics
- Ethanol
- Saccharomyces cerevisiae
- Fermentation
- Directed Molecular Evolution
- Saccharomyces cerevisiae Proteins
