Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Angiotensin II Infusion Does Not Cause Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Rats.

Journal of vascular research - 1 Jan 2018

Phillips Evan H, Chang Mandy S, Gorman Sydney, Qureshi Hamna J, Ejendal Karin F K, Kinzer-Ursem Tamara L, Blaize A Nicole, Goergen Craig J

Abstract excerpt

The apolipoprotein E-deficient (apoE-/-) mouse model has advanced our understanding of cardiovascular disease mechanisms and experimental therapeutics. This spontaneous model recapitulates aspects of human atherosclerosis, and allows for the development of dissecting abdominal aortic aneurysms (AAAs) when combined with angiotensin II. We characterized apoE-/- rats and hypothesized that, similar to mice, they...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin II
Share to Aorta, Abdominal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aortic Aneurysm, Abdominal

Share to Aortic Dissection

Share to Atherosclerosis

Share to Gene Knockout Techniques

Share to Rats, Transgenic

Share to Ultrasonography, Doppler

Source

Open in PubMed Open full text

Identifiers

PMID: 29166645
DOI: 10.1159/000484086
PMCID: PMC5829005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Angiotensin II Infusion Does Not Cause Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Rats.PMID 29166645Read ↗

Cardiovascular functional phenotypes and pharmacological responses in apolipoprotein E deficient mice.Semantic proximity Read ↗

Transcriptional profiling and network analysis of the murine angiotensin II-induced abdominal aortic aneurysmSemantic proximity Read ↗

Pathophysiology of abdominal aortic aneurysms: insights from the elastase-induced model in mice with different genetic backgrounds.Semantic proximity Read ↗

Whole genome expression analysis within the angiotensin II-apolipoprotein E deficient mouse model of abdominal aortic aneurysmSemantic proximity Read ↗

Inhibition or deletion of angiotensin II type 1 receptor suppresses elastase-induced experimental abdominal aortic aneurysms.Semantic proximity Read ↗

Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice.Semantic proximity Read ↗

Elevated Plasma Levels of LDL Cholesterol Promote Dissecting Thoracic Aortic Aneurysms in Angiotensin II-Induced Mice.Semantic proximity Read ↗

Differential gender- and species-specific formation of aneurysms using a novel method of inducing abdominal aortic aneurysms.Semantic proximity Read ↗

Mouse models of abdominal aortic aneurysms.Semantic proximity Read ↗

Vascular ultrasound for <i>in vivo</i> assessment of arterial pathologies in a murine model of atherosclerosis and aortic aneurysmSemantic proximity Read ↗

New insights into the role of angiotensin-converting enzyme obtained from the analysis of genetically modified mice.Semantic proximity Read ↗

Angiotensin II Induces Abdominal Aortic Branch Aneurysms in <i> Fibrillin-1 <sup>C1041G/+</sup> </i> MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.