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The Agr Quorum Sensing System Represses Persister Formation through Regulation of Phenol Soluble Modulins in Staphylococcus aureus

7 Nov 2017

Abstract excerpt

The opportunistic pathogen Staphylococcus aureus has become an increasing threat to public health. Its pathogenicity is an expression of both virulence and persister formation.While the Agr quorum sensing (QS) system is a master regulator of S. aureus virulence, its dysfunction has been frequently reported to promote bacteremia and mortality in clinical infections. Here we show that the Agr system is involved in...

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PMID: 29163457
DOI: 10.3389/fmicb.2017.02189

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