Article
In vitro characterization of CD133lo cancer stem cells in Retinoblastoma Y79 cell line.
BMC cancer - 21 Nov 2017
Nair Rohini M, Balla Murali Ms, Khan Imran, Kalathur Ravi Kiran Reddy, Kondaiah Paturu, Vemuganti Geeta K
Abstract excerpt
BACKGROUND: Retinoblastoma (Rb), the most common childhood intraocular malignant tumor, is reported to have cancer stem cells (CSCs) similar to other tumors. Our previous investigation in primary tumors identified the small sized cells with low CD133 (Prominin-1) and high CD44 (Hyaluronic acid receptor) expression to be putative Rb CSCs using flow cytometry (FSClo/SSClo/CD133lo/CD44hi). With this preliminary...
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