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Evaluation of Cancer Stem Cells in Patient-derived Xenografts of Retinoblastoma in a Chick Embryo-Chorioallontoic Membrane Model

2024-03-27

Abstract excerpt

<h4>Background: </h4> Cancer stem cells (CSCs) in most tumors, including retinoblastoma (Rb), are associated with tumor initiation, metastasis, and drug resistance. Our previous studies identified Rb CSCs as CD44+/CD133- by flowcytometry using size and phenotype. In this study, we further evaluated two prime characteristics of CSCs, i.e., chemoresistance and tumor-initiating properties using Chick embryo-Chorioall...

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Literature Corpus work: ff4e4e0c-1482-533e-8d21-807715d756f2
DOI: 10.21203/rs.3.rs-4148993/v1

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