Article

Evaluation of Cancer Stem Cells in Patient-derived Xenografts of Retinoblastoma in Chick Embryo-Chorioallontoic Membrane model

2024-03-21

Abstract excerpt

<h4>Background: </h4> Cancer Stem Cells (CSCs) in most tumors, including Retinoblastoma (Rb), are associated with tumor-initiation, metastasis, and drug resistance. Our previous studies identified Rb CSCs as CD44+/CD133- by flowcytometry using size and phenotype. In this study, we further evaluated two prime characteristics of CSC, i.e., chemoresistance and tumor-initiating properties using Chick embryo-Chorioalla...

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Literature Corpus work: ef9366bb-b418-58c3-b112-f5b6e642ccab
DOI: 10.21203/rs.3.rs-4130527/v1

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