Article
Phenotypic characterization of retinoblastoma for the presence of putative cancer stem-like cell markers by flow cytometry.
Investigative ophthalmology & visual science - 1 Apr 2009
Balla Murali M S, Vemuganti Geeta K, Kannabiran Chitra, Honavar Santosh G, Murthy Ramesh
Abstract excerpt
PURPOSE: Retinoblastoma (Rb) is an intraocular tumor that grows rapidly and poses a threat to sight and life. Similar to other tumors, there is increasing speculation that the Rb tumor also contains cancer stem-like cells that could influence the prognosis and response to therapy. This study was undertaken in an attempt to identify putative stem-like cells by characterizing different subpopulations of cells in...
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