Article
Radiotherapy modulates expression of EGFR, ERCC1 and p53 in cervical cancer.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 13 Nov 2017
de Almeida V H, de Melo A C, Meira D D, Pires A C, Nogueira-Rodrigues A, Pimenta-Inada H K, Alves F G, Moralez G, Thiago L S, Ferreira C G, Sternberg C
Abstract excerpt
Cervical cancer is a public health problem and the molecular mechanisms underlying radioresistance are still poorly understood. Here, we evaluated the modulation of key molecules involved in cell proliferation, cell cycle and DNA repair in cervical cancer cell lines (CASKI and C33A) and in malignant tissues biopsied from 10 patients before and after radiotherapy. The expression patterns of epidermal growth factor...
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