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Article

Increased expression of GRP94 protein is associated with decreased sensitivity to X-rays in cervical cancer cell lines

1 Jan 2005

Abstract excerpt

PURPOSE: Radiation therapy is one of the standard treatments for cervical cancer. Glucose regulated protein 94 (GRP94) is a molecular chaperone, which increases in amount after X-ray irradiation. This study examined the involvement of GRP94 in radio-resistance in human cervical cancer cells. MATERIALS AND METHODS: Seven human cervical carcinoma cell lines (HeLa, SKG-I, SKG-IIIb, QG-U, Caski, SiHa and C33A) were...

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PMID: 16368648
DOI: 10.1080/09553000500434727

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