Article
Excision repair cross complementation group 1 immunohistochemical expression predicts objective response and cancer-specific survival in patients treated by Cisplatin-based induction chemotherapy for locally advanced head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2007
Handra-Luca Adriana, Hernandez Juana, Mountzios Giannis, Taranchon Estelle, Lacau-St-Guily Jean, Soria Jean-Charles, Fouret Pierre
Abstract excerpt
PURPOSE: To assess the correlation of excision repair cross complementation group 1 (ERCC1) immunohistochemical expression with objective tumor response and cancer-specific survival in patients with locally advanced head and neck squamous cell carcinoma treated with cisplatin-based induction chemotherapy. EXPERIMENTAL DESIGN: The initial cohort was composed of 107 patients who were treated from 1992 to 1996 by an...
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