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Article

Investigation of Radiosensitivity Gene Signatures in Cancer Cell Lines

22 Jan 2014

Abstract excerpt

Intrinsic radiosensitivity is an important factor underlying radiotherapy response, but there is no method for its routine assessment in human tumours. Gene signatures are currently being derived and some were previously generated by expression profiling the NCI-60 cell line panel. It was hypothesised that focusing on more homogeneous tumour types would be a better approach. Two cell line cohorts were used...

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PMID: 24466029
DOI: 10.1371/journal.pone.0086329

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