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Article

Involvement of the Mab21l1 gene in calvarial osteogenesis.

Differentiation; research in biological diversity - 1 Jan 2000

Nguyen Dan, Yamada Ryuichi, Yoshimitsu Nodoka, Oguri Akira, Kojima Takuya, Takahashi Naoki

Abstract excerpt

The Mab-21 gene family is crucial for animal development. A deficiency in the Mab-21 genes associates with several defects, including skeletal malformation in mice and humans. In this study, we observed that mice lacking Mab21l1 displayed an unclosed fontanelle, suggesting impaired calvarial bone development. Cells isolated from the calvaria of these mice showed a greater osteoblast differentiation potential as...

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Identifiers

PMID: 29156428
DOI: 10.1016/j.diff.2017.11.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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