Article
Common genetic polymorphisms in pre-microRNAs and risk of cervical squamous cell carcinoma.
Molecular carcinogenesis - 1 Jul 2011
Zhou Bin, Wang Kana, Wang Yanyun, Xi Mingrong, Zhang Zhu, Song Yaping, Zhang Lin
Abstract excerpt
MicroRNAs (miRNAs) function as gene regulator and they participate in diverse biological pathways. Common single nucleotide polymorphisms (SNPs) in pre-microRNAs may change their property through altering miRNAs expression and/or maturation. We conducted a pilot study to test whether SNPs in pre-microRNAs were associated with cervical squamous cell carcinoma (CSCC). Genotypes of three SNPs in pre-miRNAs...
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