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Article

Polymorphisms in inflammasome genes and risk of asthma in Brazilian children.

Molecular immunology - 1 Jan 2018

Leal Vinicius Nunes Cordeiro, Genov Isabel Rugue, Mallozi Márcia C, Solé Dirceu, Pontillo Alessandra

Abstract excerpt

Considering its role in inflammation and recently described "alternative" roles in epithelial homeostasis and Th1/Th2 balance, we hypothesize that inflammasome genetics could contribute to the development of asthma. Selected functional polymorphisms in inflammasome genes are evaluated in a cohort of asthmatic children and their families. Gain-of-function NLRP1 variants rs11651270, rs12150220 and rs2670660...

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Source

Identifiers

PMID: 29154202
DOI: 10.1016/j.molimm.2017.11.006

Genes

NLRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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