Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies

6 Jun 2019

Abstract excerpt

Abstract Genetic factors underlying leukocyte telomere length (LTL) may provide insights into telomere homeostasis, with direct links to disease susceptibility. Genetic evaluation of 23,096 Singaporean Chinese samples identifies 10 genome-wide loci (P < 5 × 10−8). Several of these contain candidate genes (TINF2, PARP1, TERF1, ATM and POT1) with potential roles in telomere biology and DNA repair mechanisms....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Single-cell and spatial transcriptomics
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31171785
DOI: 10.1038/s41467-019-10443-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studiesPMID 31171785Read ↗

Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population.Semantic proximity Read ↗

Genetic and clinical determinants of telomere lengthSemantic proximity Read ↗

Genome-wide association study of telomere length among South Asians identifies a second RTEL1 association signal.Semantic proximity Read ↗

Genomic, phenomic, and geographic associations of leukocyte telomere length in the United StatesSemantic proximity Read ↗

Leukocyte telomere length, cancer incidence and all‐cause mortality among Chinese adults: Singapore Chinese Health StudySemantic proximity Read ↗

Genomic, phenomic and geographic associations of leukocyte telomere length in the United States.Semantic proximity Read ↗

Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: a report from the female lung cancer consortium in Asia.Semantic proximity Read ↗

Unraveling the causal genes and transcriptomic determinants of human telomere lengthSemantic proximity Read ↗

Genome wide association and linkage analyses identified three loci—4q25, 17q23.2, and 10q11.21—associated with variation in leukocyte telomere length: the Long Life Family StudySemantic proximity Read ↗

Polygenic basis and biomedical consequences of telomere length variationSemantic proximity Read ↗

Genetically determined telomere length and its association with chronic obstructive pulmonary disease and interstitial lung disease in biobank Japan: A Mendelian randomization studySemantic proximity Read ↗

Polygenic basis and biomedical consequences of telomere length variationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.