Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of the Transmembrane Protein IQGAP3 Is Associated with Poor Survival of Patients with Gastric Cancer.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2018

Oue Naohide, Yamamoto Yuji, Oshima Takashi, Asai Ryuichi, Ishikawa Akira, Uraoka Naohiro, Sakamoto Naoya, Sentani Kazuhiro, Yasui Wataru

Abstract excerpt

OBJECTIVE: Spheroid colony formation is a useful method of cancer stem cell (CSC) characterization. We previously showed that the IQ motif containing the GTPase-activating protein 3 gene (IQGAP3) is upregulated in spheroid body-forming gastric cancer (GC) cells compared with parental cells. We investigated IQGAP3 expression in GC. METHODS: IQGAP3 protein expression was analyzed by immunohistochemistry in 165 GC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gastric Mucosa
Share to GTPase-Activating Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mucins

Share to Neoplastic Stem Cells

Share to RNA Interference

Share to Spheroids, Cellular

Share to Stomach Neoplasms

Share to Up-Regulation

Source

Identifiers

PMID: 29131081
DOI: 10.1159/000481890

Genes

IQGAP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of the Transmembrane Protein IQGAP3 Is Associated with Poor Survival of Patients with Gastric Cancer.PMID 29131081Read ↗

DDIT3 modulates cancer stemness in gastric cancer by directly regulating CEBPβSemantic proximity Read ↗

Induction of KIFC1 expression in gastric cancer spheroidsSemantic proximity Read ↗

Overexpression of KIF11 in Gastric Cancer with Intestinal Mucin Phenotype.Semantic proximity Read ↗

M i R ‐876‐3p regulates cisplatin resistance and stem cell‐like properties of gastric cancer cells by targeting TMED 3Semantic proximity Read ↗

Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancersSemantic proximity Read ↗

Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homoeostasis and repairSemantic proximity Read ↗

Dihydropyrimidinase-like 3 facilitates malignant behavior of gastric cancer.Semantic proximity Read ↗

IGF2BP3 functions as a potential oncogene and is a crucial target of miR-34a in gastric carcinogenesisSemantic proximity Read ↗

siRNA-mediated knockdown of ID1 disrupts Nanog- and Oct-4-mediated cancer stem cell-likeness and resistance to chemotherapy in gastric cancer cellsSemantic proximity Read ↗

STAT3 is Overactivated in Gastric Cancer Stem-Like Cells.Semantic proximity Read ↗

PTBP3 contributes to the metastasis of gastric cancer by mediating CAV1 alternative splicingSemantic proximity Read ↗

Role of IQGAP1 in Head and Neck CarcinogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.