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DDIT3 modulates cancer stemness in gastric cancer by directly regulating CEBPβ

19 Mar 2020

Abstract excerpt

OBJECTIVES: Cancer stem cells (CSCs) have been identified to correlate with the initiation and metastasis of tumours, and DNA damage-inducible transcript 3 (DDIT3) is associated with the poor prognosis in gastric cancer (GC). However, whether DDIT3 mediates CSCs stemness in GC is still unclear. METHODS: Microarray analysis and Gene Ontology (GO) were conducted to identify the differentially expressed genes in GC...

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PMID: 32189359
DOI: 10.1111/jphp.13243

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