Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+ and Follicular Phenotypes.

Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2017

Wheaton Joshua D, Yeh Chen-Hao, Ciofani Maria

Abstract excerpt

Regulatory T cells (Tregs) adopt specialized phenotypes defined by coexpression of lineage-defining transcription factors, such as RORγt, Bcl-6, or PPARγ, alongside Foxp3. These Treg subsets have unique tissue distributions and diverse roles in maintaining organismal homeostasis. However, despite extensive functional characterization, the factors driving Treg specialization are largely unknown. In this article,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Germinal Center
Share to Immunization
Share to Interleukin-6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphopoiesis

Share to Nuclear Receptor Subfamily 1, Group F, Member 3

Share to Specific Pathogen-Free Organisms

Share to T-Lymphocyte Subsets

Share to T-Lymphocytes, Regulatory

Source

Open in PubMed Open full text

Identifiers

PMID: 29127150
DOI: 10.4049/jimmunol.1701134
PMCID: PMC5728164

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+ and Follicular Phenotypes.PMID 29127150Read ↗

Deciphering the Regulatory Landscape of <i>γδ</i> T Cell Development by Single-Cell RNA-SequencingSemantic proximity Read ↗

TCF-1 negatively regulates the suppressive ability of canonical and noncanonical Tregs.Semantic proximity Read ↗

NFAT primes the human RORC locus for RORγt expression in CD4+ T cellsSemantic proximity Read ↗

Transcription factor c-Maf is a checkpoint that programs macrophages in lung cancerSemantic proximity Read ↗

TRAF6 is essential for maintenance of regulatory T cells that suppress Th2 type autoimmunity.Semantic proximity Read ↗

Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor-infiltrating T regulatory cells.Semantic proximity Read ↗

Transcription factor-driven regulation of ILC1 and ILC3Semantic proximity Read ↗

<i>TCF-7</i> is dispensable for anti-tumor response but required for persistent function of mature CD8 T cellsSemantic proximity Read ↗

An NF-κB Transcription-Factor-Dependent Lineage-Specific Transcriptional Program Promotes Regulatory T Cell Identity and Function.Semantic proximity Read ↗

TCF-7 differentially regulates CD4 T cells mediated alloimmunitySemantic proximity Read ↗

Type 3 regulatory T cells at the interface of symbiosisSemantic proximity Read ↗

MAFB surrogates the glucocorticoid receptor ability to induce tolerogenesis in dendritic cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.