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Article

Induced pluripotent stem cells derived from an autosomal dominant polycystic kidney disease patient carrying a PKD1 Q533X mutation.

Stem cell research - 1 Dec 2017

Lee Jia-Jung, Ho Ming-Ching, Huang Ching-Ying, Wen Cheng-Hao, Cheng Yu-Che, Hsu Yu-Hung, Hwang Daw-Yang, Lu Huai-En, Chen Hung-Chun, Hsieh Patrick C H

Abstract excerpt

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most prevalent monogenic kidney disorder leading to kidney failure. We generated induced pluripotent stem cells (iPSCs) from a 37-year-old man carrying a PKD1 Q533X mutation who suffered from kidney failure and a myocardial infarction. The iPSCs were reprogrammed from the patient's peripheral blood mononuclear cells using the Sendai virus system, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29121521
DOI: 10.1016/j.scr.2017.10.026

Genes

PKD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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