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Article

Generation of induced pluripotent stem cell PLAFMCi002-A derived from peripheral blood mononuclear cells of polycystic kidney disease patient with PKD1 mutation.

Stem cell research - 1 Dec 2020

Wang Tao, Li Jian, Xiao Yunming, Fu Bo, Wang Peng, Bai Xueyuan, Cai Guangyan, Chen Xiangmei, Li Qinggang

Abstract excerpt

Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disease, which characterized by formation and expansion of cysts within the kidney, leading to kidney failure. Thus, Peripheral blood mononuclear cells (PBMCs) were isolated from a 32-year-old male patient carrying the PKD1 compound mutations p.M3091R and p.S843P, and were reprogrammed to human induced pluripotent stem cells (iPSCs) using...

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Identifiers

PMID: 33068887
DOI: 10.1016/j.scr.2020.102039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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