Article
Successful disease-specific induced pluripotent stem cell generation from patients with kidney transplantation.
Stem cell research & therapy - 6 Dec 2011
Thatava Tayaramma, Armstrong Adam S, De Lamo Josep Genebriera, Edukulla Ramakrishna, Khan Yulia Krotova, Sakuma Toshie, Ohmine Seiga, Sundsbak Jamie L, Harris Peter C, Kudva Yogish C, Ikeda Yasuhiro
Abstract excerpt
INTRODUCTION: End-stage renal disease (ESRD) is a major public health problem. Although kidney transplantation is a viable therapeutic option, this therapy is associated with significant limitations, including a shortage of donor organs. Induced pluripotent stem (iPS) cell technology, which allows derivation of patient-specific pluripotent stem cells, could provide a possible alternative modality for kidney...
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