Article
Prevalence of binary toxin positive Clostridium difficile in diarrhoeal humans in the absence of epidemic ribotype 027.
PloS one - 1 Jan 2017
McGovern Alan M, Androga Grace O, Knight Daniel R, Watson Mark W, Elliott Briony, Foster Niki F, Chang Barbara J, Riley Thomas V
Abstract excerpt
Virulence of Clostridium difficile is primarily attributed to the large clostridial toxins A and B while the role of binary toxin (CDT) remains unclear. The prevalence of human strains of C. difficile possessing only CDT genes (A-B-CDT+) is generally low (< 5%), however, this genotype is commonly found in neonatal livestock both in Australia and elsewhere. Zoonotic transmission of C. difficile has been suggested...
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