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Article

Studying hepcidin and related pathways in osteoblasts using a mouse model with insulin receptor substrate 1‑loss of function.

Molecular medicine reports - 1 Jan 2018

Liu Jia, Qian Ling, Guo Linna, Feng Yunzhi

Abstract excerpt

Hepcidin is one of the most important proteins in iron metabolism. In the present study, its role in iron metabolism and the associated signaling pathways involved was investigated in a mouse model with insulin receptor substrate 1‑loss of function (IRS‑/‑), and osteoblasts in the iron overload condition. Protein expression levels of hepcidin, interleukin 6 (IL‑6), bone morphogenetic protein receptor 1α and...

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Source

Identifiers

PMID: 29115497
DOI: 10.3892/mmr.2017.7876

Genes

BMP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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