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Blood CDKN2A Gene Expression in Aging and Neurodegenerative Diseases

30 Jun 2021

Abstract excerpt

BACKGROUND: Cyclin-dependent kinase inhibitor 2A (CDKN2A) is an important gene in cellular senescence and aging. OBJECTIVE: This study assessed the utility of blood CDKN2A mRNA expression levels and methylation status as a potential biomarker for aging and the pathogenesis of Alzheimer's disease (AD). METHODS: The correlation between CDKN2A mRNA expression levels and age was examined in 45 healthy subjects, after...

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PMID: 34219731
DOI: 10.3233/jad-210483

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