Article
Deep Phenotypic Mapping of Bacterial Cytoskeletal Mutants Reveals Physiological Robustness to Cell Size.
Current biology : CB - 20 Nov 2017
Shi Handuo, Colavin Alexandre, Bigos Marty, Tropini Carolina, Monds Russell D, Huang Kerwyn Casey
Abstract excerpt
Size is a universally defining characteristic of all living cells and tissues and is intrinsically linked with cell genotype, growth, and physiology. Many mutations have been identified to alter cell size, but pleiotropic effects have largely hampered our ability to probe how cell size specifically affects fundamental cellular properties, such as DNA content and intracellular localization. To systematically...
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