Article
miRNA genetic variants: As potential diagnostic biomarkers for oral cancer.
Pathology, research and practice - 1 Feb 2018
Tandon Divya, Dewangan Jayant, Srivastava Sonal, Garg Vivek Kumar, Rath Srikanta Kumar
Abstract excerpt
MicroRNAs (miRNAs) comprise a novel class of small, non-coding endogenous RNAs that have a role in the plethora of regulatory activities by directing their target mRNAs for degradation or translational repression. Single nucleotide polymorphisms (SNPs) in miRNA genes can lead to alteration in mRNA expression, resulting in serious consequences. Detection of miRNA-polymorphisms can potentially improve diagnosis,...
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