Article
The association between miR-499a polymorphism and oral squamous cell carcinoma progression.
Oral diseases - 1 Mar 2015
Hou Y-Y, Lee J-H, Chen H-C, Yang C-M, Huang S-J, Liou H-H, Chi C-C, Tsai K-W, Ger L-P
Abstract excerpt
OBJECTIVE: To investigate the association of miR-499a genetic polymorphism with the risk of oral leukoplakia, oral submucous fibrosis (OSF), oral squamous cell carcinoma (OSCC), and clinicopathological outcomes of OSCC. METHODS: The genotyping of miR-499a T>C (rs3746444) using TagMan assay was conducted in two case-control studies of 1549 subjects. miR-499a-5p and miR-499a-3p were assayed using stem-loop RT-PCR...
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