The association between genetic polymorphism and the processing efficiency of miR-149 affects the prognosis of patients with head and neck squamous cell carcinoma.

doi:10.1371/journal.pone.0051606

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The association between genetic polymorphism and the processing efficiency of miR-149 affects the prognosis of patients with head and neck squamous cell carcinoma.

PloS one - 1 Jan 2012

Tu Hsi-Feng, Liu Chung-Ji, Chang Che-Lun, Wang Pei-Wen, Kao Shou-Yen, Yang Cheng-Chieh, Yu En-Hao, Lin Shu-Chun, Chang Kuo-Wei

Abstract excerpt

MicroRNAs (miRNAs) play important roles in modulating the neoplastic process of cancers including head and neck squamous cell carcinoma (HNSCC). A genetic polymorphism (rs2292832, C>T) has been recently identified in the precursor of miR-149; nevertheless its clinicopathological implications remain obscure. In this study, we showed that miR-149 is down-regulated in HNSCC compared to normal mucosa and this is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Movement

Share to Head and Neck Neoplasms

Share to In Situ Hybridization

Share to MicroRNAs

Share to Plasmids

Share to Regression Analysis

Share to Risk

Source

Open in PubMed Open full text

Identifiers

PMID: 23272122
DOI: 10.1371/journal.pone.0051606
PMCID: PMC3522737

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The association between genetic polymorphism and the processing efficiency of miR-149 affects the prognosis of patients with head and neck squamous cell carcinoma.PMID 23272122Read ↗

The association between genetic variation rs2292832 and the processing efficiency of pre-miR-149 affects the risk of breast cancerSemantic proximity Read ↗

The association between genetic variation rs2292832 and the processing efficiency of pre-mir-149 affects the risk of breast cancer.Semantic proximity Read ↗

miRNA genetic variants: As potential diagnostic biomarkers for oral cancer.Semantic proximity Read ↗

Genetic variants in selected pre-microRNA genes and the risk of squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

Lack of association between hsa-miR-149 rs2292832 polymorphism and cancer risk: a meta-analysis of 12 studies.Semantic proximity Read ↗

The association between two microRNA variants (miR-499, miR-149) and gastrointestinal cancer risk: a meta-analysis.Semantic proximity Read ↗

Pre-miRNA variants as predictors of clinical outcome in patients with squamous cell carcinomas of the nonoropharynx.Semantic proximity Read ↗

Significant association between functional microRNA polymorphisms and head and neck cancer susceptibility: a comprehensive meta-analysis.Semantic proximity Read ↗

Update on the association of miR-149 rs2292832 C>T polymorphism with gastric cancer risk: A meta-analysis study of gastrointestinal cancers.Semantic proximity Read ↗

Genetic variants in microRNAs predict non-small cell lung cancer prognosis in Chinese female population in a prospective cohort study.Semantic proximity Read ↗

Single nucleotide polymorphisms of MIR-149 gene rs2292832 contributes to the risk of hepatocellular carcinoma, but not overall cancer: a meta-analysis.Semantic proximity Read ↗

Lack of association between miR-149 C>T polymorphism and cancer susceptibility: a meta-analysis based on 4,677 cases and 4,830 controls.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.