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Article

Interaction between job stress and the BDNF Val66Met polymorphism affects depressive symptoms in Chinese healthcare workers.

Journal of affective disorders - 15 Aug 2018

He Shu-Chang, Wu Shuang, Wang Chao, Du Xiang-Dong, Yin Guangzhong, Jia Qiufang, Zhang Yingyang, Wang Li, Soares Jair C, Zhang Xiang Yang

Abstract excerpt

BACKGROUND: Chronic exposure to job-related stress can lead to depression and BDNF polymorphism may play an important role in this process. The role of the stress × BDNF Val66Met interaction in depression has been studied widely using childhood stress, but few studies have utilized chronic stress in adulthood as a moderator. This study was to examine the chronic stress × BDNF Val66Met interaction in job-related...

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Source

Identifiers

PMID: 29734099
DOI: 10.1016/j.jad.2018.04.089

Genes

BDNF
SDS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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