Article
Developmental features of DNA methylation during activation of the embryonic zebrafish genome
25 Jul 2012
Abstract excerpt
BACKGROUND: Zygotic genome activation (ZGA) occurs at the mid-blastula transition (MBT) in zebrafish and is a period of extensive chromatin remodeling. Genome-scale gametic demethylation and remethylation occurs after fertilization, during blastula stages, but how ZGA relates to promoter DNA methylation states is unknown. Using methylated DNA immunoprecipitation coupled to high-density microarray hybridization,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
