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Article

Characterization of the deubiquitination activity and substrate specificity of the chicken ubiquitin-specific protease 1/USP associated factor 1 complex.

PloS one - 1 Jan 2017

Zheng Hainan, Wang Mengyun, Zhao Chengcheng, Wu Shanli, Yu Peifeng, Lü Yan, Wang Tiedong, Ai Yongxing

Abstract excerpt

Deubiquitinases (DUBs) are essential regulators of intracellular processes involving ubiquitin (Ub) modification. The human DUB ubiquitin-specific protease 1 (hUSP1) interacts with human USP-associated factor 1 (hUAF1), and helps to regulate processes such as DNA damage repair. Previously, we identified a chicken USP1 homologue (chUSP1) during an investigation into the properties of Marek's disease virus (MDV)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29091922
DOI: 10.1371/journal.pone.0186535
PMCID: PMC5665528

Genes

ISG15
NEDD8
SUMO1
SUMO2
SUMO3
USP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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