Article
Gene-gene interactions of CFH and LOC387715/ARMS2 with Korean exudative age-related macular degeneration patients.
Ophthalmic genetics - 1 Sept 2013
Kim Yeong Hoon, Kim Hyun-Seok, Mok Jee Won, Joo Choun-Ki
Abstract excerpt
PURPOSE: To evaluate the association and interaction of single nucleotide polymorphisms in CFH and LOC387715/ARMS2 with age-related macular degeneration (AMD) in a Korean population. METHODS: A total of 114 exudative AMD patients and 240 normal subjects participated in the study. PCR and direct sequencing were used to screen SNPs in the CFH and in the LOC387715/ARMS2. Genotype and haplotype analyses were...
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