Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hereditary persistence of hemoglobin F is protective against red cell sickling. A case report and brief review

16 Oct 2017

Abstract excerpt

Fetal hemoglobin (HbF) is a physiologic protein tetramer that is crucial for a developing fetus to survive in utero. Maternal hemoglobin has a relatively lower affinity for oxygen, and thus allows for an efficient transfer of oxygen from maternal to fetal blood. In addition to fulfilling a critical physiologic role, HbF is also known to alleviate symptoms of sickle-cell disease (SCD). The concentration of HbF...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood groups and transfusion
Share to Hemoglobinopathies and Related Disorders
Share to Iron Metabolism and Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29079125
DOI: 10.1016/j.hemonc.2017.09.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hereditary persistence of hemoglobin F is protective against red cell sickling. A case report and brief reviewPMID 29079125Read ↗

Fetal Hemoglobin in Sickle Hemoglobinopathies: High HbF Genotypes and PhenotypesSemantic proximity Read ↗

Fetal haemoglobin levels and haematological characteristics of compound heterozygotes for haemoglobin S and deletional hereditary persistence of fetal haemoglobinSemantic proximity Read ↗

[Genetically based states of elevated quantity of foetal haemoglobin (Hb F) in healthy individuals and patients].Semantic proximity Read ↗

The Natural History of Hb S/Hereditary Persistence of Fetal Hemoglobin in 13 Children from the State of Minas Gerais, Brazil.Semantic proximity Read ↗

Genetic architecture of hemoglobin F controlSemantic proximity Read ↗

Fetal hemoglobin in sickle cell anemiaSemantic proximity Read ↗

Evaluation of HPFH and δβ-thalassemia mutations in a Brazilian group with high Hb F levels.Semantic proximity Read ↗

Quantitative analysis of erythrocytes containing fetal hemoglobin (F cells) in children with sickle cell disease.Semantic proximity Read ↗

Association between BCL11A, HSB1L-MYB, and XmnI γG-158 (C/T) gene polymorphism and hemoglobin F level in Egyptian sickle cell disease patients.Semantic proximity Read ↗

HbF/F-cell and the Phenotype of Sickle Cell DiseaseSemantic proximity Read ↗

The genetic dissection of fetal haemoglobin persistence in sickle cell disease in NigeriaSemantic proximity Read ↗

Heterogeneity of fetal hemoglobin production in adult red blood cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.