Article
QuaDMutEx: quadratic driver mutation explorer.
BMC bioinformatics - 24 Oct 2017
Bokhari Yahya, Arodz Tomasz
Abstract excerpt
BACKGROUND: Somatic mutations accumulate in human cells throughout life. Some may have no adverse consequences, but some of them may lead to cancer. A cancer genome is typically unstable, and thus more mutations can accumulate in the DNA of cancer cells. An ongoing problem is to figure out which mutations are drivers - play a role in oncogenesis, and which are passengers - do not play a role. One way of...
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