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Murine Bone Marrow Mesenchymal Stromal Cells Respond Efficiently to Oxidative Stress Despite the Low Level of Heme Oxygenases 1 and 2.

Antioxidants & redox signaling - 10 Jul 2018

Nowak Witold Norbert, Taha Hevidar, Kachamakova-Trojanowska Neli, Stępniewski Jacek, Markiewicz Joanna Agata, Kusienicka Anna, Szade Krzysztof, Szade Agata, Bukowska-Strakova Karolina, Hajduk Karolina, Klóska Damian, Kopacz Aleksandra, Grochot-Przęczek Anna, Barthenheier Kathrin, Cauvin Camille, Dulak Józef, Józkowicz Alicja

Abstract excerpt

AIMS: Mesenchymal stromal cells (MSCs) are heterogeneous cells from adult tissues that are able to differentiate in vitro into adipocytes, osteoblasts, or chondrocytes. Such cells are widely studied in regenerative medicine. However, the success of cellular therapy depends on the cell survival. Heme oxygenase-1 (HO-1, encoded by the Hmox1 gene), an enzyme converting heme to biliverdin, carbon monoxide, and Fe2+,...

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Identifiers

PMID: 29065700
DOI: 10.1089/ars.2017.7097
PMCID: PMC6003402

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MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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