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Article

Cytolytic toxin production by Staphylococcus aureus is dependent upon the activity of the protoheme IX farnesyltransferase.

Scientific reports - 23 Oct 2017

Stevens Emily, Laabei Maisem, Gardner Stewart, Somerville Greg A, Massey Ruth C

Abstract excerpt

Staphylococcus aureus is a medically important pathogen with an abundance of virulence factors that are necessary for survival within a host, including the production of cytolytic toxins. The regulation of toxin production is mediated by the Agr quorum sensing system, and a poorly defined post-exponential growth phase signal independent of Agr. As part of a recent genome wide association study (GWAS) to identify...

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Identifiers

PMID: 29062030
DOI: 10.1038/s41598-017-14110-8
PMCID: PMC5653856

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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