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Article

Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases.

Antioxidants & redox signaling - 10 Jan 2014

Muñoz-Lobato Fernando, Rodríguez-Palero María Jesús, Naranjo-Galindo Francisco José, Shephard Freya, Gaffney Christopher J, Szewczyk Nathaniel J, Hamamichi Shusei, Caldwell Kim A, Caldwell Guy A, Link Chris D, Miranda-Vizuete Antonio

Abstract excerpt

AIMS: Cells have developed quality control systems for protection against proteotoxicity. Misfolded and aggregation-prone proteins, which are behind the initiation and progression of many neurodegenerative diseases (ND), are known to challenge the proteostasis network of the cells. We aimed to explore the role of DNJ-27/ERdj5, an endoplasmic reticulum (ER)-resident thioredoxin protein required as a disulfide...

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Identifiers

PMID: 23641861
DOI: 10.1089/ars.2012.5051
PMCID: PMC3887457

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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