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Article

HIC2 regulates isoform switching during maturation of the cardiovascular system.

Journal of molecular and cellular cardiology - 1 Jan 2018

Dykes Iain M, van Bueren Kelly Lammerts, Scambler Peter J

Abstract excerpt

Physiological changes during embryonic development are associated with changes in the isoform expression of both myocyte sarcomeric proteins and of erythrocyte haemoglobins. Cell type-specific isoform expression of these genes also occurs. Although these changes appear to be coordinated, it is unclear how changes in these disparate cell types may be linked. The transcription factor Hic2 is required for normal...

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Share to Cardiovascular System
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Kruppel-Like Transcription Factors

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Source

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Identifiers

PMID: 29061339
DOI: 10.1016/j.yjmcc.2017.10.007
PMCID: PMC5807030

Genes

HIC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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