Article
Developmental expression of cardiac myosin-binding protein C in Xenopus.
Development genes and evolution - 1 Feb 2002
Duan Li-Juan, George Miranda E, Drysdale Thomas A
Abstract excerpt
We have isolated the Xenopus homologue of cardiac myosin-binding protein C ( cMyBP-C) and describe its expression during early embryogenesis. cMyBP-C is expressed in both somites and heart at the time these tissues differentiate. Expression in the somites declines in older tadpoles. There is a high degree of conservation in residues where mutations causing hypertrophic cardiomyopathy have been identified in humans.
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