Article
The two actin-interacting protein 1 genes have overlapping and essential function for embryonic development in Caenorhabditis elegans.
Molecular biology of the cell - 1 Jul 2011
Ono Shoichiro, Nomura Kazumi, Hitosugi Sadae, Tu Domena K, Lee Jocelyn A, Baillie David L, Ono Kanako
Abstract excerpt
Disassembly of actin filaments by actin-depolymerizing factor (ADF)/cofilin and actin-interacting protein 1 (AIP1) is a conserved mechanism to promote reorganization of the actin cytoskeleton. We previously reported that unc-78, an AIP1 gene in the nematode Caenorhabditis elegans, is required for organized assembly of sarcomeric actin filaments in the body wall muscle. unc-78 functions in larval and adult muscle,...
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