Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inflammasome-mediated autoinflammatory disorders.

Postgraduate medicine - 1 Sept 2010

Wilson Shruti P, Cassel Suzanne L

Abstract excerpt

The nucleotide-binding domain leucine-rich repeat containing (NLR) family of receptors are members of the innate immune system, and have a critical role in host defense. These molecules are key to driving inflammatory responses to abnormal cellular conditions. Many NLRs serve this role on activation by forming a multiprotein complex called an inflammasome. The inflammasome drives the processing and release of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis
Share to Cryopyrin-Associated Periodic Syndromes
Share to Familial Mediterranean Fever

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to NLR Family, Pyrin Domain-Containing 3 Protein

Share to NLR Proteins

Share to Nod2 Signaling Adaptor Protein

Share to Receptors, Interleukin-1

Share to Vitiligo

Source

Open in PubMed Open full text

Identifiers

PMID: 20861596
DOI: 10.3810/pgm.2010.09.2209
PMCID: PMC3648991

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inflammasome-mediated autoinflammatory disorders.PMID 20861596Read ↗

Immunology in clinic review series; focus on autoinflammatory diseases: role of inflammasomes in autoinflammatory syndromes.Semantic proximity Read ↗

The NLRP3 and Pyrin Inflammasomes: Implications in the Pathophysiology of Autoinflammatory DiseasesSemantic proximity Read ↗

A clinical update on inflammasomopathies.Semantic proximity Read ↗

The role of the inflammasome in patients with autoinflammatory diseases.Semantic proximity Read ↗

[Interleukin-1, inflammasome and autoinflammatory diseases].Semantic proximity Read ↗

The hereditary autoinflammatory disorders uncovered.Semantic proximity Read ↗

Pathogenic NLRP3 mutants forms constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β productionSemantic proximity Read ↗

Interleukin-1, inflammasomes, autoinflammation and the skinSemantic proximity Read ↗

Inflammasomes and Their Roles in Health and DiseaseSemantic proximity Read ↗

Deregulated inflammasome signaling in disease.Semantic proximity Read ↗

Cryopyrin-associated periodic syndromes: background and therapeuticsSemantic proximity Read ↗

The inflammasome, autoinflammatory diseases, and gout.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.