Article
CCDC6: the identity of a protein known to be partner in fusion.
International journal of cancer - 1 Apr 2018
Cerrato Aniello, Merolla Francesco, Morra Francesco, Celetti Angela
Abstract excerpt
Coiled Coil Domain Containing 6 gene, CCDC6, was initially isolated as part of a tumorigenic DNA originated by the fusion of CCDC6 with the tyrosine kinase of RET receptor, following a paracentric inversion of chromosome 10. For a long time, CCDC6 has been considered as an accidental partner of the RET protooncogene, providing the promoter and the first 101 aa necessary for the constitutive activation of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
