Article
Regulatory network and targeted interventions for CCDC family in tumor pathogenesis.
Cancer letters - 1 Jul 2023
Liu Zhen, Yan Weiwei, Liu Shaohua, Liu Zhan, Xu Ping, Fang Weiyi
Abstract excerpt
CCDC (coiled-coil domain-containing) is a coiled helix domain that exists in natural proteins. There are about 180 CCDC family genes, encoding proteins that are involved in intercellular transmembrane signal transduction and genetic signal transcription, among other functions. Alterations in expression, mutation, and DNA promoter methylation of CCDC family genes have been shown to be associated with the...
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