Article
HIV-1 genetic diversity in Argentina and early diagnosis of perinatal infection.
Medicina - 1 Jan 2006
Aulicino Paula C, Gómez Carrillo Manuel, Kopka Julieta, Mangano Andrea M, Ovejero Marcelo, Sen Luisa
Abstract excerpt
HIV-1 diagnosis of perinatally exposed children is usually performed by molecular biology-based methods, allowing the direct detection of the virus. Thus, HIV-1 genomic variability within and across strains plays a major role in relation to the sensitivity of these tests, often leading to misdiagnosis. We describe the performance of an in-house multiplex nested PCR (nPCR) for early detection of HIV-1 infection in...
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