Article
Drug resistance prevalence and HIV-1 variant characterization in the naive and pretreated HIV-1-infected paediatric population in Madrid, Spain.
The Journal of antimicrobial chemotherapy - 1 Oct 2011
de Mulder Miguel, Yebra Gonzalo, Martín Leticia, Prieto Luís, Mellado María José, Rojo Pablo, Muñoz-Fernández María Ángeles, Jiménez de Ory Santiago, Ramos José Tomas, Holguín Africa
Abstract excerpt
BACKGROUND: Drug resistance mutations affect antiretroviral therapy (ART) effectiveness in HIV-1-infected children, compromising long-term therapy. HIV-1 variants and drug resistance mutations were identified in HIV-infected children from Madrid, Spain. METHODS: Patients from the Madrid cohort of HIV-infected children (1993-2009) with available pol sequences or infected samples stored at the Spanish HIV-1 BioBank...
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