Article
Trends in Drug Resistance Prevalence, HIV-1 Variants and Clinical Status in HIV-1-infected Pediatric Population in Madrid: 1993 to 2015 Analysis.
The Pediatric infectious disease journal - 1 Mar 2018
Rojas Sánchez Patricia, Domínguez Sara, Jiménez De Ory Santiago, Prieto Luis, Rojo Pablo, Mellado Pepa, Navarro Marisa, Delgado Rafael, Ramos José Tomas, Holguín África
Abstract excerpt
BACKGROUND: The expanded use of long-term antiretroviral treatments in infected children may exacerbate the problem of drug resistance mutations selection, which can compromise treatment efficiency. OBJECTIVE: We describe the temporal trends of HIV drug resistance mutations and the HIV-1 variants during 23 years (1993 to March 2016) in the Madrid cohort of HIV-infected children and adolescents. METHODS: We...
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