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Article

Luma is not essential for murine cardiac development and function.

Cardiovascular research - 1 Mar 2018

Stroud Matthew J, Fang Xi, Zhang Jianlin, Guimarães-Camboa Nuno, Veevers Jennifer, Dalton Nancy D, Gu Yusu, Bradford William H, Peterson Kirk L, Evans Sylvia M, Gerace Larry, Chen Ju

Abstract excerpt

AIMS: Luma is a recently discovered, evolutionarily conserved protein expressed in mammalian heart, which is associated with the LInker of Nucleoskeleton and Cytoskeleton (LINC) complex. The LINC complex structurally integrates the nucleus and the cytoplasm and plays a critical role in mechanotransduction across the nuclear envelope. Mutations in several LINC components in both humans and mice result in various...

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Share to Arrhythmogenic Right Ventricular Dysplasia
Share to Cytoskeleton

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertrophy, Left Ventricular

Share to Mechanotransduction, Cellular

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Share to Myocytes, Cardiac

Share to Myocytes, Smooth Muscle

Source

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Identifiers

PMID: 29040414
DOI: 10.1093/cvr/cvx205
PMCID: PMC6019056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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