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Article

Generation and Analysis of Striated Muscle Selective LINC Complex Protein Mutant Mice.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Stroud Matthew J, Fang Xi, Veevers Jennifer, Chen Ju

Abstract excerpt

The linker of nucleoskeleton and cytoskeleton (LINC) complex mediates intracellular cross talk between the nucleus and the cytoplasm. In striated muscle, the LINC complex provides structural support to the myocyte nucleus and plays an essential role in regulating gene expression and mechanotransduction. A wide range of cardiac and skeletal myopathies have been linked to mutations in LINC complex proteins. Studies...

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Identifiers

PMID: 30141050
DOI: 10.1007/978-1-4939-8691-0_18
PMCID: PMC6887482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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