Article
Apparently "BRCA-related" breast and ovarian cancer patient with germline TP53 mutation.
The breast journal - 1 Jan 2000
Janavičius Ramūnas, Andrėkutė Kristina, Mickys Ugnius, Rudaitis Vilius, Brasiūnienė Birutė, Griškevičius Laimonas
Abstract excerpt
Germline TP53 gene mutations are associated with complex cancer predisposition syndrome, the Li--Fraumeni syndrome, and are not as rare as were previously thought. Currently, the identification of Li--Fraumeni syndrome is mostly based on a conformance to descriptive criteria, which recently were amended to include wider spectrum of malignancies. The presence of very young age-onset breast cancers in TP53...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.